Police are investigating a serious single-vehicle crash on Highland Lakes Road, Apsley this morning (Tuesday, 19 August).

The Mistubishi Express van, driven by a 63-year-old man, was travelling along Highland Lakes Road just before 6.00am when the vehicle left the road.

The man was airlifted to the Royal Hobart Hospital in a serious condition.

The cause of the crash is still under investigation.

Police would like to speak to anyone who observed the Mitsubishi van driving in the Highland Lakes area prior to the crash.

Anyone with information or dash cam footage is asked to contact police on 131 444 or report through Crime Stoppers Tasmania at crimestopperstas.com.au or on 1800 333 000. Please quote ESCAD: 026-19082025.